inate immunity

Last reviewed 11/2020

Innate immunity is basic and nonspecific.

  • represents the first line of defence to an intruding pathogen
  • response is unable to “memorise” the same said pathogen should the body be exposed to it in the future

It includes:

  • phagocytic cells (macrophages, neutrophils; more generally, antigen-presenting cells (APCs))
  • natural killer cells (NK cells)
  • mast cells
  • dendritic cells
  • eosinophils
  • barriers (e.g. skin)
  • antimicrobial compounds, for example,
    • complement
    • acute phase proteins
    • interferons